ISBN: 9783639080896

Anabolic androgenic substances (AAS) increase musclemass, reduce total body fat and induce a positivenitrogen balance, resulting in higherperformance. Therefore the use of AAS in competit… More...

Anabolic androgenic substances (AAS) increase musclemass, reduce total body fat and induce a positivenitrogen balance, resulting in higherperformance. Therefore the use of AAS in competitivesports is of extreme attractivness but strictlyillegal. In animal husbandry the application of AASis legal in some countries but forbidden in theEU. Also in medical therapies anabolic agents areapplied. The residue analysis methods for AAS are mostly basedon confirmation of suspected samples via substanceidentification by mass spectrometry. It is alsoknown that AAS can influence mRNA expression ofspecific genes.The aim of this thesis was to proof the possibilityto detect AAS treatment via mRNA expression analysis.With the identification of biomarkers foranabolic agents using qRT-PCR, a gene expressionpattern for AAS and metabolic pathways should beidentified. First tissue specific biomarkers and effects onmetabolic pathways could be detected. Thesesbiomarkers can be taken to establish a screeningpattern for anabolic agents.Therefore, first steps toward a new screening methodfor anabolic agents could be done, helping touncover abuses of anabolic agents in the future. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Naturwissenschaften / Biologie, [PU: VDM Verlag Dr. Müller, Saarbrücken]<

ISBN: 9783639080896

Paperback, [PU: VDM Verlag Dr. Mueller e.K.], Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher … More...

Paperback, [PU: VDM Verlag Dr. Mueller e.K.], Anabolic androgenic substances (AAS) increase muscle mass, reduce total body fat and induce a positive nitrogen balance, resulting in higher performance. Therefore the use of AAS in competitive sports is of extreme attractivness but strictly illegal. In animal husbandry the application of AAS is legal in some countries but forbidden in the EU. Also in medical therapies anabolic agents are applied. The residue analysis methods for AAS are mostly based on confirmation of suspected samples via substance identification by mass spectrometry. It is also known that AAS can influence mRNA expression of specific genes. The aim of this thesis was to proof the possibility to detect AAS treatment via mRNA expression analysis. With the identification of biomarkers for anabolic agents using qRT-PCR, a gene expression pattern for AAS and metabolic pathways should be identified. First tissue specific biomarkers and effects on metabolic pathways could be detected. Theses biomarkers can be taken to establish a screening pattern for anabolic agents. Therefore, first steps toward a new screening method for anabolic agents could be done, helping to uncover abuses of anabolic agents in the future., Physiology<

2008, ISBN: 3639080890

[EAN: 9783639080896], Neubuch, [PU: VDM Verlag Dr. Müller|VDM Verlag Dr. Müller e.K.], BIOLOGIE ANABOLIKA ANABOLISCHE STEROIDE, Anabolic androgenic substances (AAS) increase musclemass, r… More...

[EAN: 9783639080896], Neubuch, [PU: VDM Verlag Dr. Müller|VDM Verlag Dr. Müller e.K.], BIOLOGIE ANABOLIKA ANABOLISCHE STEROIDE, Anabolic androgenic substances (AAS) increase musclemass, reduce total body fat and induce a positivenitrogen balance, resulting in higherperformance. Therefore the use of AAS in competitivesports is of extreme attractivness but strictlyillegal. In animal h., Books<

ISBN: 9783639080896

Fnac.com : Livraison gratuite et - 5% sur tous les livres. Possible New Screening Methods for Anabolic Agents - Livre. Découvrez des nouveautés, des coups de cœur, des avis d'internautes,… More...

Fnac.com : Livraison gratuite et - 5% sur tous les livres. Possible New Screening Methods for Anabolic Agents - Livre. Découvrez des nouveautés, des coups de cœur, des avis d'internautes, … Livre - Livre, Vdm Verlag Dr Mueller E K<