2012, ISBN: 9783659229817

[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for i… More...

[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for its potential as a cell-based therapeutic strategy for cartilage regeneration in partial thickness chondral defects. A photopolymerizable N-methacrylate glycol chitosan (MGC) was employed to form an in situ gel that was embedded with two formulations of growth factor-loaded microspheres and human adipose-derived stem cells (ASC). The polymeric microspheres were used as a delivery vehicle for the controlled release of growth factors to stimulate differentiation of the ASC towards the chondrocyte lineage. Bone morphogenetic protein-6 (BMP-6) and transforming growth factor-b3 (TGF-b3) were delivered at 5 ng/day at highly bioactive states. The ratio of collagen type II to I per cell was significantly higher for ASC chondrogenesis induced by the sustained release of BMP-6 and TGF-b3 in MGC gels than that of non-induced ASC or with soluble growth factor administration in the culture media. Thus, the co-delivery of growth factor-loaded microspheres and ASC in MGC gels successfully induced ASC chondrogenesis and is a promising strategy for cartilage repair., DE, [SC: 0.00], Neuware, gewerbliches Angebot, H: 220mm, B: 150mm, T: 11mm, 220, [GW: 308g], Selbstabholung und Barzahlung, PayPal, offene Rechnung, Banküberweisung, Internationaler Versand<

ISBN: 9783659229817

Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for its potential as a cell-based therapeutic strategy for cartilage regene… More...

Co-delivery of embedded growth factor-loaded microspheres and adult stem cells in a hydrogel matrix was studied for its potential as a cell-based therapeutic strategy for cartilage regeneration in partial thickness chondral defects. A photopolymerizable N-methacrylate glycol chitosan (MGC) was employed to form an in situ gel that was embedded with two formulations of growth factor-loaded microspheres and human adipose-derived stem cells (ASC). The polymeric microspheres were used as a delivery vehicle for the controlled release of growth factors to stimulate differentiation of the ASC towards the chondrocyte lineage. Bone morphogenetic protein-6 (BMP-6) and transforming growth factor-b3 (TGF-b3) were delivered at 5 ng/day at highly bioactive states. The ratio of collagen type II to I per cell was significantly higher for ASC chondrogenesis induced by the sustained release of BMP-6 and TGF-b3 in MGC gels than that of non-induced ASC or with soluble growth factor administration in the culture media. Thus, the co-delivery of growth factor-loaded microspheres and ASC in MGC gels successfully induced ASC chondrogenesis and is a promising strategy for cartilage repair. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Medizin / Gesundheit<

2012, ISBN: 9783659229817

Erscheinungsdatum: 10/2012, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Stem cell and growth factor delivery vehicles for cartilage repair, Titelzusatz: Co-delivery of g… More...

Erscheinungsdatum: 10/2012, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Stem cell and growth factor delivery vehicles for cartilage repair, Titelzusatz: Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair, Autor: Sukarto, Abby, Verlag: LAP Lambert Academic Publishing, Sprache: Englisch, Rubrik: Alternative Medizin // Naturmedizin, Homöopathie, Seiten: 220, Informationen: Paperback, Gewicht: 344 gr, Verkäufer: averdo Belletristik<

2012, ISBN: 3659229814

Buch, gebundene Ausgabe, 220 S., Beilagen: Paperback, Erschienen: 2012 Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair, … More...

Buch, gebundene Ausgabe, 220 S., Beilagen: Paperback, Erschienen: 2012 Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair, LAP Lambert Academic Publishing<

ISBN: 3659229814

Stem cell and growth factor delivery vehicles for cartilage repair ab 79 EURO Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage r… More...

Stem cell and growth factor delivery vehicles for cartilage repair ab 79 EURO Co-delivery of growth factor-loaded microspheres and human adipose stem cells in a gel matrix for cartilage repair Medien > Bücher<