2003, ISBN: 3211407766

[EAN: 9783211407769], Neubuch, [SC: 11.57], [PU: Springer Vienna], ALZHEIMER'SDISEASE; CHROMOSOM; DOWNSYNDROME; EMOTION; MICROARRAY; REGULATION; SYNDROM; BIOLOGICALFUNCTIONS; CHROMOSOME21… More...

[EAN: 9783211407769], Neubuch, [SC: 11.57], [PU: Springer Vienna], ALZHEIMER'SDISEASE; CHROMOSOM; DOWNSYNDROME; EMOTION; MICROARRAY; REGULATION; SYNDROM; BIOLOGICALFUNCTIONS; CHROMOSOME21; TRANSCRIPTION, Druck auf Anfrage Neuware -'Advances in Down Syndrome Research' represents updated research in several areas of Down Syndrome (DS).A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes. 260 pp. Englisch, Books<

2003, ISBN: 3211407766

[EAN: 9783211407769], Neubuch, [SC: 11.8], [PU: Springer Vienna], ALZHEIMER'SDISEASE; CHROMOSOM; DOWNSYNDROME; EMOTION; MICROARRAY; REGULATION; SYNDROM; BIOLOGICALFUNCTIONS; CHROMOSOME21;… More...

[EAN: 9783211407769], Neubuch, [SC: 11.8], [PU: Springer Vienna], ALZHEIMER'SDISEASE; CHROMOSOM; DOWNSYNDROME; EMOTION; MICROARRAY; REGULATION; SYNDROM; BIOLOGICALFUNCTIONS; CHROMOSOME21; TRANSCRIPTION, Druck auf Anfrage Neuware -'Advances in Down Syndrome Research' represents updated research in several areas of Down Syndrome (DS).A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes. 260 pp. Englisch, Books<

ISBN: 9783211407769

Advances in Down Syndrome Research represents updated research in several areas of Down Syndrome (DS).A new promising animal model of DS is reported and this opens new opportunities to st… More...

Advances in Down Syndrome Research represents updated research in several areas of Down Syndrome (DS).A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes. | Advances in Down Syndrome Research by Gert Lubec Paperback | Indigo Chapters Books > Health > Medical > Internal Medicine P10178, Gert Lubec<

2003, ISBN: 9783211407769

[ED: Softcover], [PU: Springer, Wien], "Advances in Down Syndrome Research" represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is repor… More...

[ED: Softcover], [PU: Springer, Wien], "Advances in Down Syndrome Research" represents updated research in several areas of Down Syndrome (DS). A new promising animal model of DS is reported and this opens new opportunities to study pathomechanisms and pharmacological approaches as it is more than difficult to carry out studies in humans and the clinical features are highly variable. In terms of biology, cell cycle and stem cell studies and in terms of biochemistry, relevance of studies on a specific protein kinase, channels, transporters, superoxide dismutase, antioxidant system, chromosome assembly factor and other important biological structures are provided. And again, the gene dosage hypothesis is addressed and although the vast majority of chromosome 21 gene products is unchanged in fetal DS brain, a few specific chromosome 21 encoded structures including transcription factors are indeed overexpressed although findings in fetal DS are different from those in adult DS brain when Alzheimer-like neuropathology supervenes. 2003. x, 242 S. 29 SW-Abb. 279 mm Versandfertig in 6-10 Tagen, DE, Neuware, gewerbliches Angebot, Offene Rechnung (Vorkasse vorbehalten)<

2003, ISBN: 3211407766

Softcover reprint of the original 1st ed. 2003 Kartoniert / Broschiert Genetik, Medizin, Klinische und Innere Medizin, Pädiatrie, Pathologie, Neurowissenschaften, Molekularbiologie, Alz… More...

Softcover reprint of the original 1st ed. 2003 Kartoniert / Broschiert Genetik, Medizin, Klinische und Innere Medizin, Pädiatrie, Pathologie, Neurowissenschaften, Molekularbiologie, Alzheimer's disease; Chromosom; Emotion; Microarray; Regulation; Syndrom; biological functions; chromosome 21; transcription, mit Schutzumschlag neu, [PU:Springer Vienna; Springer Wien]<