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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
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F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 539011516

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Buch (fremdspr.) gebundene Ausgabe 31.05.1990 Bücher>Fremdsprachige Bücher>Englische Bücher, Springer US, .199

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - Alvarez-Leefmans, F. J. / Russell, John M.
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Alvarez-Leefmans, F. J. / Russell, John M.:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - used book

ISBN: 9780306434266

ID: 854460

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Alvarez-Leefmans, F. J. / Russell, John M., Plenum Publishing Corporation

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
book is out-of-stock
(*)
F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 835068998

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer Us

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - International Brain Research Organizatio
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International Brain Research Organizatio:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - hardcover

1990, ISBN: 9780306434266

ID: 996524796

Springer, 1990. 1990. Hardcover. Used; Good. No dust jacket. Fast Dispatch. Expedited UK Delivery Available. Excellent Customer Service. Bookbarn International Inventory #2446911, Springer, 1990

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J.Alvarez- Leefmans; John M. Russell
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F.J.Alvarez- Leefmans; John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - hardcover

1990, ISBN: 9780306434266

ID: 1086048

1990 ed., Hardcover, Buch, [PU: Kluwer Academic/Plenum Publishers]

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