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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
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F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 539011516

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Buch (fremdspr.) gebundene Ausgabe 31.05.1990 Bücher>Fremdsprachige Bücher>Englische Bücher, Springer US, .199

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
book is out-of-stock
(*)
F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 58279464

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Bücher > Fremdsprachige Bücher > Englische Bücher gebundene Ausgabe 31.05.1990 Buch (fremdspr.), Springer, .199

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
book is out-of-stock
(*)
F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 835068998

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer Us

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No. 11433082. Shipping costs:, Versandfertig in 3 - 5 Tagen, DE. (EUR 0.00)
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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - F.J. Alvarez-Leefmans#John M. Russell
book is out-of-stock
(*)
F.J. Alvarez-Leefmans#John M. Russell:
Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - new book

ISBN: 9780306434266

ID: 739417287

This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther­ modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem­ brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener­ alized and virtually all cells were thought to have a very high P Cl and a ther­ modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer

New book Thalia.de
No. 11433082 Shipping costs:, Versandfertig in 3 - 5 Tagen, DE (EUR 0.00)
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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - Collectif
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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - used book

ISBN: 9780306434266

ID: 446622730_us

Livre, [PU: Consultants Bureau, and Kluwer Academic (NY)]

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