ISBN: 9781461449546
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, v… More...
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ISBN: 9781461449546
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, v… More...
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2012, ISBN: 9781461449546
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ISBN: 9781461449546
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, v… More...
ISBN: 9781461449546
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, v… More...
2012
ISBN: 9781461449546
eBooks, eBook Download (PDF), Auflage, [PU: Springer-Verlag], [ED: 1], Springer-Verlag, 2012
2012, ISBN: 9781461449546
eBooks, eBook Download (PDF), 2013, [PU: Springer New York], Springer New York, 2012
2012, ISBN: 9781461449546
[ED: 1], Auflage, eBook Download (PDF), eBooks, [PU: Springer-Verlag]
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Details of the book - Biophysics of RNA Folding
EAN (ISBN-13): 9781461449546
ISBN (ISBN-10): 1461449545
Publishing year: 2012
Publisher: Springer-Verlag
236 Pages
Language: eng/Englisch
Book in our database since 2012-03-29T03:19:58+01:00 (London)
Detail page last modified on 2023-03-20T16:36:38+00:00 (London)
ISBN/EAN: 1461449545
ISBN - alternate spelling:
1-4614-4954-5, 978-1-4614-4954-6
Alternate spelling and related search-keywords:
Book author: russell, russel, russ, mao
Book title: folding
Information from Publisher
Author: Rick Russell
Title: Biophysics for the Life Sciences; Biophysics of RNA Folding
Publisher: Springer; Springer US
238 Pages
Publishing year: 2012-12-09
New York; NY; US
Language: English
106,99 € (DE)
110,00 € (AT)
130,00 CHF (CH)
Available
VI, 238 p.
EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; B; Biomedical Research; Biophysics; Biochemistry; Nucleic Acid; Biomedical and Life Sciences; Biophysik; Biochemie; Technische Anwendung von Biomaterialien; BB
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns. In addition to the fundamental features of RNA folding, the central experimental and computational approaches in the field are presented with an emphasis on their individual strengths and limitations, and how they can be combined to be more powerful than any method alone; these approaches include NMR, single molecule fluorescence, site-directed spin labeling, structure mapping, comparative sequence analysis, graph theory, course-grained 3D modeling, and more. This volume will be of interest to professional researchers and advanced students entering the field of RNA folding.
Introduction.- Comparative Analysis of the Higher-order Structure of RNA.- Graph Applications to RNA Structure and Function.- Prediction and Coarse-Grained Modeling of RNA Structures.- RNA Folding Using Site-Directed Spin Labeling.- The RNA Recognition Motif and Messenger RNA.- Memory Effects in RNA folding dynamics revealed by single molecule fluorescence.- An integrated picture of HDV ribozyme catalysis.- Combining biochemical and structural information to model RNA-protein complex assembly.- Following RNA Folding From Local and Global Perspectives.- The Roles of Chaperones in RNA Folding.
Structured RNAs are everywhere, functioning throughout gene expression with key roles ranging from catalysis to regulation. New functional RNAs are being discovered all the time; in fact, it is now clear that a much greater fraction of eukaryotic genomes is devoted to coding for RNA than protein. Many of these RNAs must traverse complex energy landscapes to find their functional three-dimensional structures. Along the way, they may encounter native and non-native folding intermediates, chaperone proteins, and assemble with partner proteins.
This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns. In addition to the fundamental features of RNA folding, the central experimental and computational approaches in the field are presented with an emphasis on their individual strengths and limitations, and how they can be combined to be more powerful than any method alone; these approaches include NMR, single molecule fluorescence, site-directed spin labeling, structure mapping, comparative sequence analysis, graph theory, course-grained 3D modeling, and more. This volume will be of interest to professional researchers and advanced students entering the field of RNA folding.
Focuses on concepts and methods relating to developments in study of RNA folding Unique approach integrates methods and topics, rather than having an initial series of chapters focused solely on methods Comprehensive and up-to-date survey of biophysical approaches to the dynamic field of RNA biology Includes supplementary material: sn.pub/extras
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