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Protein-Protein Interactions as New Drug Targets - Klussmann, Enno / Scott, John (eds.)
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Klussmann, Enno / Scott, John (eds.):

Protein-Protein Interactions as New Drug Targets - hardcover

2008, ISBN: 9783540728429

[ED: Hardcover], [PU: Springer / Springer Berlin Heidelberg / Springer, Berlin], Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess gr… More...

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Protein-Protein Interactions as New Drug Targets - Klussmann, Enno Scott, John
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Klussmann, Enno Scott, John:

Protein-Protein Interactions as New Drug Targets - First edition

2008, ISBN: 9783540728429

Hardcover

[ED: Gebunden], [PU: Springer Berlin Heidelberg], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. With contributions by numerous expertsDi… More...

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Klussmann, Enno und John Scott:
Protein-Protein Interactions as New Drug Targets 2008 - used book

2008

ISBN: 9783540728429

2008 Neubindung 4289096/12 Versandkostenfreie Lieferung Scaffolding Proteins,proteins,Protein-Protein Interactions,Small Molecules,Peptide Disruptors,Compartimentalisation,, [PU:Springer … More...

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Protein-Protein Interactions as New Drug Targets - Klussmann, Enno und John Scott
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Klussmann, Enno und John Scott:
Protein-Protein Interactions as New Drug Targets - used book

2008, ISBN: 9783540728429

[PU: Springer Berlin], Neubindung 4289096/12, DE, [SC: 0.00], gebraucht; sehr gut, gewerbliches Angebot, 2008, Banküberweisung, Kreditkarte, PayPal, Internationaler Versand

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Klussmann E.:
Protein-Protein Interactions As New Drug Targets (Hb) - used book

ISBN: 9783540728429

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Details of the book
Protein-Protein Interactions as New Drug Targets
Author:
Title:
ISBN:

9783540728429


Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

Details of the book - Protein-Protein Interactions as New Drug Targets


EAN (ISBN-13): 9783540728429
ISBN (ISBN-10): 3540728422
Hardcover
Publishing year: 2008
Publisher: Springer Berlin
512 Pages
Weight: 0,862 kg
Language: eng/Englisch

Book in our database since 2007-10-07T17:55:29+01:00 (London)
Detail page last modified on 2024-04-14T11:16:35+01:00 (London)
ISBN/EAN: 9783540728429

ISBN - alternate spelling:
3-540-72842-2, 978-3-540-72842-9
Alternate spelling and related search-keywords:
Book author: klussmann, haldane, klußmann, john scott, riek saleem, bode, klüssmann
Book title: drug interactions handbook, handbook experimental pharmacology, 473 target, new handbook, interaction, protein protein interactions

Information from Publisher

Author: Enno Klussmann; John Scott
Title: Handbook of Experimental Pharmacology; Protein-Protein Interactions as New Drug Targets
Publisher: Springer; Springer Berlin
512 Pages
Publishing year: 2008-06-23
Berlin; Heidelberg; DE
Language: English
320,99 € (DE)
329,99 € (AT)
354,00 CHF (CH)
Available
XV, 512 p.

BB; Hardcover, Softcover / Medizin/Pharmazie; Pharmakologie; Verstehen; Medizin, Gesundheit; Compartimentalisation; Peptide Disruptors; Protein-Protein Interactions; Scaffolding Proteins; Small Molecules; proteins; Pharmacology; Cell Biology; Medical Biochemistry; Biomedical Research; Zellbiologie (Zytologie); Medizinische Chemie, Pharmazeutische Chemie; Medizinische Forschung; EA; BC

Organization of Scaffolds.- A-Kinase Anchoring Proteins as the Basis for cAMP Signaling.- Arrestins as Multi-Functional Signaling Adaptors.- Role of Ena/VASP Proteins in Homeostasis and Disease.- Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy.- Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?.- Scaffolding Proteins and Cellular Signalling.- PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases.- G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains.- Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design.- Compartmentalised MAPK Pathways.- Dynamic Protein Complexes Regulate NF-?B Signaling.- An Oncogenic Hub: ?-Catenin as a Molecular Target for Cancer Therapeutics.- A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling.- Cell Type-Specific Anchoring.- Scaffolding Proteins in Cardiac Myocytes.- Molecular Architecture of Signal Complexes Regulating Immune Cell Function.- Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework.- Interference with Protein-Protein Interaction Sites as a New Pharmacological Concept.- Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies.- Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition.- Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors.- Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs.- Direct AKAP-Mediated Protein-Protein Interactions as Potential Drug Targets.
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