2015, ISBN: 3838150899

[EAN: 9783838150895], Neubuch, [PU: Südwestdeutscher Verlag Für Hochschulschriften], nach der Bestellung gedruckt Neuware -This book describes two different projects associated with the c… More...

[EAN: 9783838150895], Neubuch, [PU: Südwestdeutscher Verlag Für Hochschulschriften], nach der Bestellung gedruckt Neuware -This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural carbohydrates from readily available starting materials. After a comprehensive introduction to indium chemistry and stereoselective aldol reactions, two new methodologies are presented which complement the synthetic arsenal available to the carbohydrate chemist. The indium mediated allylation of unprotected carbohydrates was applied in the synthesis of acetamido-heptoses and octoses which are constituents of the aminoglycoside antibiotics Apramycin and Destomycin. Furthermore, a new approach for the incorporation of fluorine into carbohydrates is described. Amino acid building blocks were chain-elongated via a titanium mediated aldol addition, finally furnishing amino-, fluoro-functionalised pentoses and hexoses. These compounds are of high interest not only concerning their potential antimicrobial activity but also their usefulness in elucidating fundamental biological processes such as antigen-antibody aggregation. 196 pp. Englisch, Books<

2015, ISBN: 9783838150895

[ED: Softcover], [PU: Südwestdeutscher Verlag für Hochschulschriften], This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural ca… More...

[ED: Softcover], [PU: Südwestdeutscher Verlag für Hochschulschriften], This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural carbohydrates from readily available starting materials. After a comprehensive introduction to indium chemistry and stereoselective aldol reactions, two new methodologies are presented which complement the synthetic arsenal available to the carbohydrate chemist. The indium mediated allylation of unprotected carbohydrates was applied in the synthesis of acetamido-heptoses and octoses which are constituents of the aminoglycoside antibiotics Apramycin and Destomycin. Furthermore, a new approach for the incorporation of fluorine into carbohydrates is described. Amino acid building blocks were chain-elongated via a titanium mediated aldol addition, finally furnishing amino-, fluoro-functionalised pentoses and hexoses. These compounds are of high interest not only concerning their potential antimicrobial activity but also their usefulness in elucidating fundamental biological processes such as antigen-antibody aggregation. 2015. 196 S. 220 mm Versandfertig in 6-10 Tagen, DE, [SC: 0.00], Neuware, gewerbliches Angebot, Offene Rechnung (Vorkasse vorbehalten)<

ISBN: 9783838150895

Paperback, [PU: Sudwestdeutscher Verlag Fur Hochschulschriften AG], This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural carbo… More...

Paperback, [PU: Sudwestdeutscher Verlag Fur Hochschulschriften AG], This book describes two different projects associated with the chemical (de novo) synthesis of rare and unnatural carbohydrates from readily available starting materials. After a comprehensive introduction to indium chemistry and stereoselective aldol reactions, two new methodologies are presented which complement the synthetic arsenal available to the carbohydrate chemist. The indium mediated allylation of unprotected carbohydrates was applied in the synthesis of acetamido-heptoses and octoses which are constituents of the aminoglycoside antibiotics Apramycin and Destomycin. Furthermore, a new approach for the incorporation of fluorine into carbohydrates is described. Amino acid building blocks were chain-elongated via a titanium mediated aldol addition, finally furnishing amino-, fluoro-functionalised pentoses and hexoses. These compounds are of high interest not only concerning their potential antimicrobial activity but also their usefulness in elucidating fundamental biological processes such as antigen-antibody aggregation., Chemistry<

ISBN: 9783838150895

Hardcover

Metals in Carbohydrate Synthesis ab 63.99 € als Taschenbuch: Indium and Titanium mediated Chain Elongations of Chiral Pool Building Blocks. Aus dem Bereich: Bücher, English, International… More...

Metals in Carbohydrate Synthesis ab 63.99 € als Taschenbuch: Indium and Titanium mediated Chain Elongations of Chiral Pool Building Blocks. Aus dem Bereich: Bücher, English, International, Englische Taschenbücher, Medien > Bücher nein Taschenbuch, Südwestdeutscher Verlag für Hochschulschriften<