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Mesenchymal Stromal Cells
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Mesenchymal Stromal Cells - new book

2013, ISBN: 9781461457114

Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress h… More...

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Mesenchymal Stromal Cells - Peiman Hematti; Peiman Hematti; Armand Keating; Armand Keating
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Mesenchymal Stromal Cells - First edition

2013, ISBN: 9781461457114

Biology and Clinical Applications, eBooks, eBook Download (PDF), Auflage, [PU: Humana Press], [ED: 1], Humana Press, 2013

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Peiman Hematti; Armand Keating:
Mesenchymal Stromal Cells - new book

2013

ISBN: 9781461457114

Biology and Clinical Applications, eBooks, eBook Download (PDF), 2013, [PU: Springer New York], Seiten: 695, Springer New York, 2013

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Mesenchymal Stromal Cells - Peiman Hematti;  Peiman Hematti;  Armand Keating;  Armand Keating
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Peiman Hematti; Peiman Hematti; Armand Keating; Armand Keating:
Mesenchymal Stromal Cells - new book

2013, ISBN: 9781461457114

Biology and Clinical Applications, [ED: 2], Auflage, eBook Download (PDF), eBooks, [PU: Humana Press]

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Mesenchymal Stromal Cells - Peiman Hematti; Armand Keating
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Peiman Hematti; Armand Keating:
Mesenchymal Stromal Cells - new book

2013, ISBN: 9781461457114

Biology and Clinical Applications, eBooks, eBook Download (PDF), 2013, [PU: Springer New York], Springer New York, 2013

Shipping costs:Download sofort lieferbar. (EUR 0.00)

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Details of the book

Details of the book - Mesenchymal Stromal Cells


EAN (ISBN-13): 9781461457114
ISBN (ISBN-10): 1461457114
Publishing year: 2013
Publisher: Humana Press
695 Pages
Language: eng/Englisch

Book in our database since 2012-09-30T09:44:59+01:00 (London)
Detail page last modified on 2022-06-07T17:52:26+01:00 (London)
ISBN/EAN: 9781461457114

ISBN - alternate spelling:
1-4614-5711-4, 978-1-4614-5711-4


Information from Publisher

Author: Peiman Hematti; Armand Keating
Title: Stem Cell Biology and Regenerative Medicine; Mesenchymal Stromal Cells - Biology and Clinical Applications
Publisher: Humana; Springer US
695 Pages
Publishing year: 2013-01-16
New York; NY; US
Printed / Made in
Language: English
192,59 € (DE)
198,00 € (AT)
220,50 CHF (CH)
Available
XXVI, 695 p. 61 illus., 40 illus. in color.

EA; E107; eBook; Nonbooks, PBS / Biologie/Genetik, Gentechnik; Entwicklungsbiologie; Verstehen; Biology; Cell; Clinical Application; Hematti; Keating; MSC; Mesenchymal; Stromal; B; Stem Cells; Cell Biology; Biotechnology; Stem Cell Biology; Cell Biology; Biotechnology; Biomedical and Life Sciences; Zellbiologie (Zytologie); Biotechnologie; BB

Mesenchymal Stromal Cell (MSC) biology has been studied for more than 4 decades and the cells have been investigated for potential clinical applications for more than 15 years. Progress has become exponential over the past decade due mainly to the broad therapeutic potential of these cells.   However, MSC studies have also been subject to controversy and increasing scrutiny as new mechanisms of action are reported and ever-expanding therapeutic applications pursued. In this book, leading authorities from all over the world, who are actively involved in this field, provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with MSCs.  This cutting edge book is the ideal resource for scientists and clinicians interested in pursuing an important and rapidly developing field of research that will eventually help patients and address urgent unmet medical needs.

Features include:

MSCs in regenerative medicine: A perspective.- MSCs: Changing hypotheses, paradigms, and controversies on mechanisms of action in repairing tissues.- MSCs:  the need to rethink.- Characterization of MSCs: From early studies to the present.- MSCs as therapeutics.- MSC niche for hematopoiesis.- Immunomodulatory properties of MSCs.- MSCs and the innate immune system: A balancing act.- MSCs: paracrine effects.- Cross-talk between MSCs and their environments.- Human MSCs from bone marrow, umbilical cord blood and adipose tissue: all the same?.- MSCs in solid tumors and hematological malignancies: from basic biology to therapeutic potential.- MSC studies in large animal Models.- Defining the potential of MSCs with a prenatal large animal Model .- Bench-to-bedside development of MSC based therapies: A multidisciplinary approach.- GMP production of MSCs.- MSCs: The USA regulatory perspective.- MSCs: Clinical applications and European regulatory aspects.- Stem cell treatments around the world: boon or bane?.- Safety issues in MSC therapy.- In Vivo imaging of MSCs.- National Heart, Lung, and Blood Institute support of cellular therapies regenerative medicine.- MSC therapy of inborn errors.- MSCs for enhancement of hematopoietic progenitor cell engraftment and poor graft function.- MSCs for graft-versus-host disease.- MSCs in paediatric hematopoietic stem cell transplantation.- MSCs for ex vivo expansion of umbilical cord blood cells.- MSCs for autoimmune disorders.- MSCs for induction of solid organ allograft acceptance.- MSCs for gastrointestinal disorders.- MSCs for cardiac repair.- MSCs for acute lung injury.- MSCs for diabetes.- MSCs for renal repair.- MSCs for the treatment of stroke, spinal cord injury, and traumatic brain injury: From bench work to clinical trials.- MSCs in reconstructive surgery.- MSCs in orthopedic surgery.- Adipose tissue derived MSCs: Moving to the clinic.

is Associate Professor of Medicine, Pediatrics, Surgery and Biomedical Engineering at the University of Wisconsin-Madison, School of Medicine and Public Health.  He obtained his MD degree from Tehran University, School of Medicine, completed residencies in internal medicine and pediatrics at the Cleveland Clinic Foundation, and a clinical and research fellowship in hematology at National Heart, Lung, and Blood Institute of the National Institutes of Health, Bethesda, Maryland. He joined UW-Madison in 2004 as a bone marrow transplant physician and soon became the director of Clinical Hematopoietic Cell Processing Laboratory, and Director of Bone Marrow Collection, Apheresis and Processing Center, at University of Wisconsin-Hospital and Clinics. His clinical research interests are in the use of mesenchymal stromal cells for treatment of graft versus host disease and other immune dysregulation disorders, novel cellular therapies for hematological malignancies, and use of bone marrow stem cells in regenerative medicine. His laboratory research focuses on investigating the immune modulatory properties of mesenchymal stromal cells with a focus on their interactions with macrophages. He is collaborating with many investigators from a wide range of disciplines at the local, national, and international levels studying the potential of mesenchymal stromal cells in many different in vitro and in vivo pre-clinical models with the ultimate goal of using these cells in clinical trials. He is co-principal investigator of UW-Madison “Production Assistance for Cellular Therapies” (PACT) award from NHLBI-NIH, and 2012-chair of PACT Education Steering Committee. He has been recently selected to serve as the American Society of Hematology representative to the AABB Cellular Therapies Standards Program Unit. Dr. Hematti is on editorial board of several journals including Experimental Hematology and Cytotherapy. He has numerous manuscripts and book chapters published in the field of mesenchymal stromal cells.

Armand Keating, MD, FRCP(C Peiman Hematti, MD

Chapters written by investigators who have made significant contributions to the field

Covers of the biology of MSCs, latest understanding of mechanisms of action, and role in tissue homeostasis and regeneration

Identifies the potential of MSCs in proceeding from bench to bedside from regulatory , GMP production, ethical and safety aspects

Critical analysis of clinical studies and the potential of MSCs to treat a wide variety of human diseases and tissues



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