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Patrekar, Prasad / Dalvi, Vishal / Patil, Chandrakant:Solubility enhancement of diacerin using cyclodextrin - Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers
- Paperback 2012, ISBN: 9783848486458
[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with var… More...
[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility., DE, [SC: 0.00], Neuware, gewerbliches Angebot, H: 220mm, 84, Selbstabholung und Barzahlung, PayPal, offene Rechnung, Banküberweisung, Internationaler Versand<
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Prasad Patrekar:Solubility enhancement of diacerin using cyclodextrin
- Paperback ISBN: 9783848486458
[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with vario… More...
[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility., DE, [SC: 2.00], Neuware, gewerbliches Angebot, 220x150x5 mm, 84, [GW: 142g], PayPal, offene Rechnung, Banküberweisung, sofortueberweisung.de, Internationaler Versand<
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Solubility enhancement of diacerin using cyclodextrin
- new bookISBN: 9783848486458
Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have … More...
Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Medizin / Pharmazie<
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Prasad Patrekar/ Vishal Dalvi/ Chandrakant Patil:Solubility enhancement of diacerin using cyclodextrin
- Paperback ISBN: 3848486458
Solubility enhancement of diacerin using cyclodextrin ab 48.99 € als Taschenbuch: Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers. Aus dem Bereich: Büche… More...
Solubility enhancement of diacerin using cyclodextrin ab 48.99 € als Taschenbuch: Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers. Aus dem Bereich: Bücher, Wissenschaft, Medizin, Medien > Bücher, LAP Lambert Academic Publishing<
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Patrekar, Prasad; Dalvi, Vishal; Patil, Chandrakant:Solubility enhancement of diacerin using cyclodextrin Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers
- new book 2012, ISBN: 3848486458
Kartoniert / Broschiert, mit Schutzumschlag neu, [PU:LAP Lambert Academic Publishing]
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