Stevan Pecic:Aporphines - MDMA Antagonists and AChE Inhibitors
- Paperback 2005, ISBN: 9783847344919
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of … More...
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of large amounts of serotonin, noradrenaline and dopamine in the brain. MDMA also acts directly on a number of receptors, including 5-HT2A receptors. There is considerable evidence that 5-HT2A antagonists can modulate behavioral and physiological effects of MDMA in animals. Nantenine an aporphine alkaloid ex Nandina domestica has been reported to block and reverse a range of behavioral and physiological effects of MDMA in mice. In this book is shown synthesis and design of a library of novel analogs in order to investigate the structural requirements for nantenine s 5-HT2A activity. To elucidate possible binding modes of these compounds and to determine the correlation with our binding data, we built a 5-HT2A homology model based on a bovine rhodopsin template and then performed docking/scoring experiments. In the second part of the book, nantenine as well as a number of flexible analogs were evaluated for acetylcholinesterase (AChE) inhibitory activity in a microplate spectrophotometric assays based on Ellman s method.- Besorgungstitel - vorauss. Lieferzeit 3-5 Tage., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 220x150x17 mm, 276, [GW: 429g], Banküberweisung, Offene Rechnung, Kreditkarte, PayPal, Offene Rechnung (Vorkasse vorbehalten), Internationaler Versand<
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Stevan Pecic:Aporphines - MDMA Antagonists and AChE Inhibitors
- Paperback 2005, ISBN: 9783847344919
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of … More...
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of large amounts of serotonin, noradrenaline and dopamine in the brain. MDMA also acts directly on a number of receptors, including 5-HT2A receptors. There is considerable evidence that 5-HT2A antagonists can modulate behavioral and physiological effects of MDMA in animals. Nantenine an aporphine alkaloid ex Nandina domestica has been reported to block and reverse a range of behavioral and physiological effects of MDMA in mice. In this book is shown synthesis and design of a library of novel analogs in order to investigate the structural requirements for nantenine s 5-HT2A activity. To elucidate possible binding modes of these compounds and to determine the correlation with our binding data, we built a 5-HT2A homology model based on a bovine rhodopsin template and then performed docking/scoring experiments. In the second part of the book, nantenine as well as a number of flexible analogs were evaluated for acetylcholinesterase (AChE) inhibitory activity in a microplate spectrophotometric assays based on Ellman s method.- Besorgungstitel - vorauss. Lieferzeit 3-5 Tage., DE, [SC: 4.99], Neuware, gewerbliches Angebot, 220x150x17 mm, 276, [GW: 429g], Banküberweisung, Offene Rechnung, Kreditkarte, PayPal, Offene Rechnung (Vorkasse vorbehalten), Internationaler Versand<
| | booklooker.deAHA-BUCH GmbH Shipping costs:Versand nach Österreich. (EUR 4.99) Details... |
(*) Book out-of-stock means that the book is currently not available at any of the associated platforms we search.
Stevan Pecic:Aporphines - MDMA Antagonists and AChE Inhibitors
- Paperback 2005, ISBN: 9783847344919
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of … More...
[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], Neuware - MDMA is a psychoactive drug which is thought to act via stimulation of secretion as well as inhibition of re-uptake of large amounts of serotonin, noradrenaline and dopamine in the brain. MDMA also acts directly on a number of receptors, including 5-HT2A receptors. There is considerable evidence that 5-HT2A antagonists can modulate behavioral and physiological effects of MDMA in animals. Nantenine an aporphine alkaloid ex Nandina domestica has been reported to block and reverse a range of behavioral and physiological effects of MDMA in mice. In this book is shown synthesis and design of a library of novel analogs in order to investigate the structural requirements for nantenine s 5-HT2A activity. To elucidate possible binding modes of these compounds and to determine the correlation with our binding data, we built a 5-HT2A homology model based on a bovine rhodopsin template and then performed docking/scoring experiments. In the second part of the book, nantenine as well as a number of flexible analogs were evaluated for acetylcholinesterase (AChE) inhibitory activity in a microplate spectrophotometric assays based on Ellman s method., DE, [SC: 5.00], Neuware, gewerbliches Angebot, 220x150x17 mm, 276, [GW: 429g], Banküberweisung, PayPal, Offene Rechnung (Vorkasse vorbehalten), Internationaler Versand<
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Stevan Pecic:Aporphines - MDMA Antagonists and AChE Inhibitors
- First edition 2014, ISBN: 9783847344919
Paperback
[ED: Kartoniert / Broschiert], [PU: LAP LAMBERT Academic Publishing], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pecic… More...
[ED: Kartoniert / Broschiert], [PU: LAP LAMBERT Academic Publishing], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Pecic Stevanis an Associate Research Scientist in the Division of Clinical Pharmacology and Experimental Therapeutics at Columbia University Medi, DE, [SC: 0.00], Neuware, gewerbliches Angebot, Taschenbuch, 276, [GW: 408g], 1. Auflage, Banküberweisung, PayPal, [CT: Medizin/Pharmazie / Sonstiges - Medizin]<
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Pecic, Stevan:Aporphines - MDMA Antagonists and AChE Inhibitors: Synthesis and Evaluation
- Paperback 2014, ISBN: 9783847344919
LAP LAMBERT Academic Publishing, Paperback, 276 Seiten, Publiziert: 2014-02-05T00:00:01Z, Produktgruppe: Book, 0.41 kg, Pharmacology, Other Branches of Medicine, Medical & Healthcare Prac… More...
LAP LAMBERT Academic Publishing, Paperback, 276 Seiten, Publiziert: 2014-02-05T00:00:01Z, Produktgruppe: Book, 0.41 kg, Pharmacology, Other Branches of Medicine, Medical & Healthcare Practitioners, Health, Family & Lifestyle, Subjects, Books, Medical Sciences A-Z, Science, Nature & Maths, Medicine & Nursing, Scientific, Technical & Medical, LAP LAMBERT Academic Publishing, 2014<
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