ISBN: 9783034887557

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word sepsis derives from the Greek meaning decay or rottenness. … More...

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word sepsis derives from the Greek meaning decay or rottenness. Tradition­ ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin­ ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon­ stration of microorganisms in the circulation has led to a new definition and under­ standing of sepsis, mainly as the systemic response of the host to an often unde­ tectable microbiological or non-microbiological process [3]. The general consensus is that cytokines are central to the inflammatory response, particularly in sepsis. It is now known that not only Gram-negative but also Gram­ positive, viral, and fungal infections initiate the complex cascades of cytokine release. Probably the most important aspect of bacterial action is the release of toxic bacterial products. In particular endotoxin from Gram-negative bacteria (see chap­ ter by Schade) and super antigens (see chapter by Neumann and Holzmann), as well as pore-forming toxins [4] from Gram-positive bacteria, induce cytokine formation. The importance of this cytokine release is evident from both diagnostic and thera­ peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome. Digital Content>E-books>Medicine>Medical Ref>Med Ref, Birkhäuser Basel Digital >16<

ISBN: 9783034887557

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word sepsis derives from the Greek meaning decay or rottenness. … More...

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word sepsis derives from the Greek meaning decay or rottenness. Tradition­ ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin­ ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon­ stration of microorganisms in the circulation has led to a new definition and under­ standing of sepsis, mainly as the systemic response of the host to an often unde­ tectable microbiological or non-microbiological process [3]. The general consensus is that cytokines are central to the inflammatory response, particularly in sepsis. It is now known that not only Gram-negative but also Gram­ positive, viral, and fungal infections initiate the complex cascades of cytokine release. Probably the most important aspect of bacterial action is the release of toxic bacterial products. In particular endotoxin from Gram-negative bacteria (see chap­ ter by Schade) and super antigens (see chapter by Neumann and Holzmann), as well as pore-forming toxins [4] from Gram-positive bacteria, induce cytokine formation. The importance of this cytokine release is evident from both diagnostic and thera­ peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome. Digital Content>E-books>Medicine>Medical Ref>Med Ref, Birkhäuser Basel Digital >16<

ISBN: 9783034887557

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness… More...

t Heinz Red! and Gunther Sch!ag Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria The word "sepsis" derives from the Greek meaning decay or rottenness. Tradition­ ally this term has been used to describe the process of infection accompanied by the host's systemic inflammatory response. Based on that understanding, previous clin­ ical studies have been designed to include only patients with positive blood cultures [1, 2]. However, the frequent occurrence of a septic response without the demon­ stration of microorganisms in the circulation has led to a new definition and under­ standing of sepsis, mainly as the systemic response of the host to an often unde­ tectable microbiological or non-microbiological process [3]. The general consensus is that cytokines are central to the inflammatory response, particularly in sepsis. It is now known that not only Gram-negative but also Gram­ positive, viral, and fungal infections initiate the complex cascades of cytokine release. Probably the most important aspect of bacterial action is the release of toxic bacterial products. In particular endotoxin from Gram-negative bacteria (see chap­ ter by Schade) and super antigens (see chapter by Neumann and Holzmann), as well as pore-forming toxins [4] from Gram-positive bacteria, induce cytokine formation. The importance of this cytokine release is evident from both diagnostic and thera­ peutic (mostly experimental) studies, and the action of cytokines may be the key to our understanding of the pathophysiology of the sepsis syndrome., Birkhäuser<

2013, ISBN: 9783034887557

Birkhäuser, Kindle Ausgabe, Auflage: 1999, 636 Seiten, Publiziert: 2013-03-11T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Medizin, Kategorien, Bücher, Pathologie, Grundlagen, Med… More...

Birkhäuser, Kindle Ausgabe, Auflage: 1999, 636 Seiten, Publiziert: 2013-03-11T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Medizin, Kategorien, Bücher, Pathologie, Grundlagen, Medizin & Gesundheitsdienste, Fachbücher, Intensivmedizin, Klinische Medizin, Infektiologie, Beschwerden & Krankheiten, Gesundheit & Medizin, Ratgeber, Fitness, Fremdsprachige Bücher, Gesundheit, Fitness & Wellness, Fremdsprachige eBooks, Kindle eBooks, Kindle-Shop, Muskuloskelettale Erkrankungen, Störungen & Krankheiten, Gesundheit, Geist & Körper, Englische eBooks, Nach Sprache, Intensivpflege, Innere Medizin, Infektionskrankheiten, Format: Kindle eBook, Redl, H. Birkhäuser, 2013<

2013, ISBN: 9783034887557

Editor: Redl, H. Birkhäuser, Kindle Edition, Auflage: 1999, 636 Seiten, Publiziert: 2013-03-11T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Illnesses & Conditions, Health Issues, … More...

Editor: Redl, H. Birkhäuser, Kindle Edition, Auflage: 1999, 636 Seiten, Publiziert: 2013-03-11T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Illnesses & Conditions, Health Issues, Health, Family & Lifestyle, Subjects, Books, General Medical Issues, Medical & Healthcare Practitioners, Infectious & Contagious Diseases, Diseases & Disorders, Internal Medicine, Surgery, Intensive Care, Accident & Emergency Medicine, Medical Sciences A-Z, Science, Nature & Maths, Medicine & Nursing, Scientific, Technical & Medical, Disorders & Diseases, Health & Fitness, Kindle eBooks, Categories, Kindle Store, Professional & Technical, Format: Kindle eBook, Birkhäuser, 2013<