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Carica papaya lipase: a versatile enantioselectivity biocatalyst - Jim Chen/ Shau-Wei Tsai
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Carica papaya lipase: a versatile enantioselectivity biocatalyst - Paperback

ISBN: 9783844317305

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*Carica papaya lipase: a versatile enantioselectivity biocatalyst* - Applications of medium engineering and substrate engineering to improving Carica papaya lipase- catalyzed kinetic reso… More...

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Jim Chen:

Carica Papaya Lipase a Versatile Enantioselectivity Biocatalyst Applications of Medium Engineering and Substrate Engineering to Improving Carica Kinetic Resolution of R, Snaproxen Esters - Paperback

2003, ISBN: 9783844317305

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Chen, Jim:
Carica Papaya Lipase: a Versatile Enantioselectivity Biocatalyst - Paperback

2011

ISBN: 9783844317305

paperback, Access codes and supplements are not guaranteed with used items. May be an ex-library book., Gebraucht, guter Zustand, [PU: LAP LAMBERT Academic Publishin]

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Carica papaya lipase: a versatile enantioselectivity biocatalyst - Jim Chen
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Jim Chen:
Carica papaya lipase: a versatile enantioselectivity biocatalyst - Paperback

2011, ISBN: 3844317309

[EAN: 9783844317305], Neubuch, [PU: LAP Lambert Academic Publishing], PRINT ON DEMAND Book; New; Fast Shipping from the UK., Books

NEW BOOK. Shipping costs: EUR 1.75 Ria Christie Collections, Uxbridge, United Kingdom [59718070] [Rating: 5 (von 5)]
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Chen, Jim, and Tsai, Shau-Wei:
Carica papaya lipase: a versatile enantioselectivity biocatalyst - Paperback

2011, ISBN: 9783844317305

Trade paperback, New., Trade paperback (US). Glued binding. 160 p., Saarbrucken, [PU: LAP Lambert Academic Publishing]

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Carica papaya lipase: a versatile enantioselectivity biocatalyst
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ISBN:

3844317309


The papaya lipase stored in the crude papain from spay-dried latex of Carica papaya has been discovered as a versatile enantioselectivity biocatalyst to obtain chiral acids by using hydrolytic resolution of their racemic esters. With adopting the enzyme screening, purification, medium engineering and substrate engineering tactics can effectively improve the ability of lipase- catalyzed hydrolysis of (R,S)-naproxen ester. By employing partially purified lipase or an appropriate organo-soluble base (ex: Triethylamine) addition in water-saturated isooctane, both have superior enhancement of lipase activity or enantioselectivity. In addition, it was also found that initial rate enhancement for (S)-ester displayed as increasing the inductive parameter (electron-withdraw capability), therefore it further implies the acylaction step must be the rate- limiting step during enzyme-catalyzed process. Besides, a novel means of applying substrate- assisted catalysis demonstrated the proton shuttle device acts as an effective tool for improving the lipase activity by forming an extra intra-molecular hydrogen bond (11.5~11.9 KJ/mol) in the transition state.

Details of the book - Carica papaya lipase: a versatile enantioselectivity biocatalyst


EAN (ISBN-13): 9783844317305
ISBN (ISBN-10): 3844317309
Hardcover
Paperback
Publishing year: 2011
Publisher: LAP LAMBERT Academic Publishing

Book in our database since 2009-07-17T04:27:40+01:00 (London)
Detail page last modified on 2023-07-12T10:49:29+01:00 (London)
ISBN/EAN: 3844317309

ISBN - alternate spelling:
3-8443-1730-9, 978-3-8443-1730-5
Alternate spelling and related search-keywords:
Book author: tsai, wei wei
Book title: papaya, wei

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