ISBN: 9781617379949
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many ca… More...
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2011, ISBN: 9781617379949
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2011, ISBN: 9781617379949
Springer, Hardcover, Auflage: 2011, 456 Seiten, Publiziert: 2011-03-03T00:00:01Z, Produktgruppe: Book, 0.85 kg, Verkaufsrang: 10885413, Oncology, Internal Medicine, Medicine, Medical Book… More...
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2011 Gebundene Ausgabe Krebs (Krankheit), Tumor / Krebs, Arznei / Arzneimittellehre, Pharmakologie, Toxikologie, Pharmacology, Cancer; cancerresearch, mit Schutzumschlag 11, [PU:Humana … More...
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ISBN: 9781617379949
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many ca… More...
2011, ISBN: 9781617379949
[ED: Gebundene Ausgabe], [PU: Springer], EAN: 9781617379949 Das Titelbild der Auflage kann abweichen. Buch mit Gebrauchsspuren und vereinzelten Knicken, Flecken oder mit Gebrauchsspuren a… More...
2011
ISBN: 9781617379949
[ED: Gebunden], [PU: Humana Press], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focuses of this volume: chemical carcinogenesis, expos… More...
2011, ISBN: 9781617379949
Springer, Hardcover, Auflage: 2011, 456 Seiten, Publiziert: 2011-03-03T00:00:01Z, Produktgruppe: Book, 0.85 kg, Verkaufsrang: 10885413, Oncology, Internal Medicine, Medicine, Medical Book… More...
2011, ISBN: 1617379948
2011 Gebundene Ausgabe Krebs (Krankheit), Tumor / Krebs, Arznei / Arzneimittellehre, Pharmakologie, Toxikologie, Pharmacology, Cancer; cancerresearch, mit Schutzumschlag 11, [PU:Humana … More...
Bibliographic data of the best matching book
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Details of the book - Chemical Carcinogenesis (Current Cancer Research)
EAN (ISBN-13): 9781617379949
ISBN (ISBN-10): 1617379948
Hardcover
Publishing year: 2011
Publisher: Springer
440 Pages
Weight: 0,809 kg
Language: eng/Englisch
Book in our database since 2007-05-03T03:55:00+01:00 (London)
Detail page last modified on 2024-03-07T10:47:00+00:00 (London)
ISBN/EAN: 1617379948
ISBN - alternate spelling:
1-61737-994-8, 978-1-61737-994-9
Alternate spelling and related search-keywords:
Book author: penning, trevor
Information from Publisher
Author: Trevor M. Penning
Title: Current Cancer Research; Chemical Carcinogenesis
Publisher: Humana; Humana Press
440 Pages
Publishing year: 2011-03-03
Totowa; NJ; US
Printed / Made in
Weight: 0,846 kg
Language: English
235,39 € (DE)
241,99 € (AT)
260,00 CHF (CH)
POD
XVI, 440 p. With 2 16 page color inserts.
BB; Cancer Research; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; Cancer; Cancer Research; Carcinogenesis; Chemical; Pharmacology/Toxicology; Cancer Biology; Pharmacology; Pharmakologie; BC; EA
This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.
1. Historical Overview of Chemical Carcinogenesis
2. Multistage Carcinogenesis
3. Tobacco Smoke Carcinogens and Lung Cancer
4. Mechanisms of Estrogen Carcinogenesis: Modulation by Botanical Natural Products
5. Heterocyclic Amines: Potential Human Carcinogens
6. Aflatoxins and Hepatocellular Carcinoma
7. Metabolic Activation of Chemical Carcinogens
8. Detoxication of Chemical Carcinogens and Chemoprevention
9. Covalent Polycyclic Aromatic Hydrocarbon-DNA Adducts, Carcinogenicity, Structure and Function
10. Oxidation and Deamination of DNA by Endogenous Sources
11. Lipid Peroxide-DNA Adducts
12. Chemical Carcinogenesis and Epigenetics
13. Nucletoide Excision Repair From Bacteria to Humans: Structure-Function Studies
14. Base Excision Repair: Role of DNA Polymerase b in Late Stage Base Excision Repair
-Alkylguanine-DNA alkyltransferase
16. By-Pass DNA Polymerases
17. Mutagenesis: The Outcome of Faulty Replication of DNA
18. p53 and Ras-Mutation
Focuses of this volume: chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action, the balance between metabolic activation to form biological reactive intermediates and their detoxification, and environmental agents that can promote tumor formation
appeals to graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research
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